In traditional medicine fruits and leaves of C. hystrix are used to relieve headaches, rheumatism, fever, to treat diabetes mellitus, hypertension, heart diseases etc.
A Malaysian team published in January 2022 (free access) a synthesis (review) of knowledge on the action of kaffir lime on metabolic disorders (diabetes, hypertension, dyslipidemia, obesity). In vitro and animal studies allow to describe favorable effects on cardiovascular and pulmonary, endocrine and enzymatic regulations, the mechanism of action against hypertension, obesity, etc.

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